We are the Bioinformatics Group of the Max Planck Institute of Molecular Cell Biology and Genetics and we are involved in bioinformatics research and service at the MPI-CBG.

Our research focus lies mainly on functional genomics and proteomics and relies on collaborative studies performed by research groups at the institute. Due to these close ties with a biological research environment, we are dedicating our efforts to the development of bioinformatics tools and databases that will help advance biological sciences.



Focus RNA interference:

    we have developed a web-based tool for the design and quality control of esiRNAs.
    • check out DEQOR!

    the RiDDLE database holds pre-calculated, DEQOR-optimized esiRNAs for human, mouse and rat! (Fly and worm are coming soon!)
    • check out RiDDLE!



Focus Functional Annotation

    the ProFAT server performs functional annotation based on weak sequence similarity and literature-based text mining (PubMed).
    • check out ProFAT!

    the HMMerThread database holds information on weakly conserved domains of entire genomes.
    • check out HMMerThread-db!